Yes, the shield is compatible with any microcontroller board with an Arduino R3 expansion slot or by using the USB connector. However, the sample applications were built for the FRDM board and the ARM mbed IoT Device Platform, and so it’s the easiest to integrate with the shield. Currently, there is no software library for Arduino itself, however. You could implement your own using the AT Command Guide on the Resources page. For using something like a Raspberry Pi, see the guide for doing so on our Quickstart page.